Tsg 101 (E303) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Tsg 101 (E303) Peptide Applications :
Blocking Background :
It is now well accepted that the transformation of a normal cell to one that is malignant can result from mutations in genes that encode proteins with key regulatory functions. Examples include the retinoblastoma gene product (Rb p110), p53, VHL and APC. Using a novel cloning strategy that allows the isolation of previously uncharacterized genes encoding selectable recessive phenotypes, an additional tumor suppressor gene has been identified. This gene, termed tsg 101 for tumor susceptibility gene 101, encodes a stathmin binding domain protein. When expression of this growth inhibitory gene is blocked in NIH/3T3 cells using antisense mRNA, the cells exhibit a transformed phenotype and are tumorigenic in SL6 mice. Alternative Name :
TSG101; AI255943. CC2 Swiss-Prot :
Q99816 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Tsg 101 (E303). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2347 Tsg 101 (E303) pAb.
Tsg 101 (E303) Peptide Applications :
Blocking Background :
It is now well accepted that the transformation of a normal cell to one that is malignant can result from mutations in genes that encode proteins with key regulatory functions. Examples include the retinoblastoma gene product (Rb p110), p53, VHL and APC. Using a novel cloning strategy that allows the isolation of previously uncharacterized genes encoding selectable recessive phenotypes, an additional tumor suppressor gene has been identified. This gene, termed tsg 101 for tumor susceptibility gene 101, encodes a stathmin binding domain protein. When expression of this growth inhibitory gene is blocked in NIH/3T3 cells using antisense mRNA, the cells exhibit a transformed phenotype and are tumorigenic in SL6 mice. Alternative Name :
TSG101; AI255943. CC2 Swiss-Prot :
Q99816 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Tsg 101 (E303). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2347 Tsg 101 (E303) pAb.
Blocking peptide available as BS2347PP