ChoKB (E324) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
ChoKB (E324) Peptide Applications :
Blocking Background :
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. Choline kinase, the initial enzyme in the sequence, plays a role in cell growth proliferation. A related protein, ChoKB (also, known as choline kinase beta), is a 395 amino acid enzyme that catalyzes the phosphorylation of choline by ATP in the presence of magnesium, thereby yielding phosphocholine and ADP. Like all choline kinases, ChoKB possesses ethanoalamine kinase activity and catalyzes the phosphorylation of ethanolamine. The gene encoding ChoKB is located less than 1 kb upstream of the CPT1B gene, suggesting that the ChoKB gene may regulate transcription CPT1B. In mice, mutations and/or deletions in the gene encoding ChoKB are the cause of hindlimb muscular dystrophy and neonatal bone deformity. Alternative Name :
Choline/ethanolamine kinase; Choline kinase beta; Short name=CK; CKB; Choline kinase-like protein; Ethanolamine kinase; Short name=EK; Ethanolamine kinase beta; EKB; choline/ethanolamine kinase beta; CKEKB; CHKB; CHETK; CHKL Swiss-Prot :
Q9Y259 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ChoKB (E324). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2377 ChoKB (E324) pAb.
ChoKB (E324) Peptide Applications :
Blocking Background :
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. Choline kinase, the initial enzyme in the sequence, plays a role in cell growth proliferation. A related protein, ChoKB (also, known as choline kinase beta), is a 395 amino acid enzyme that catalyzes the phosphorylation of choline by ATP in the presence of magnesium, thereby yielding phosphocholine and ADP. Like all choline kinases, ChoKB possesses ethanoalamine kinase activity and catalyzes the phosphorylation of ethanolamine. The gene encoding ChoKB is located less than 1 kb upstream of the CPT1B gene, suggesting that the ChoKB gene may regulate transcription CPT1B. In mice, mutations and/or deletions in the gene encoding ChoKB are the cause of hindlimb muscular dystrophy and neonatal bone deformity. Alternative Name :
Choline/ethanolamine kinase; Choline kinase beta; Short name=CK; CKB; Choline kinase-like protein; Ethanolamine kinase; Short name=EK; Ethanolamine kinase beta; EKB; choline/ethanolamine kinase beta; CKEKB; CHKB; CHETK; CHKL Swiss-Prot :
Q9Y259 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ChoKB (E324). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2377 ChoKB (E324) pAb.
Blocking peptide available as BS2377PP