MRCKβ (F1665) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
MRCKβ (F1665) Peptide Applications :
Blocking Background :
Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues. Myotonic dystrophy kinaserelated Cdc42-binding (DMPK-like) kinases-α and β (MRCK-α, β) contain a cysteine-rich motif and a putative pleckstrin homology domain. MRCKs can phosphorylate nonmuscle Myosin light chain and influences Actin-Myosin contractility. MRCK-α can phosphorylate and activate LIM kinases downstream of Cdc42, which leads to inactivation of ADF/Cofilin and to Actin cytoskeletal reorganization. MRCK-α can also influence neurite outgrowth promoted by Cdc42 and Rac. Alternative Name :
MRCKβ; CDC42BPB; KIAA1124; MRCK beta Swiss-Prot :
Q9Y5S2 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide MRCKβ (F1665). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2382 MRCKβ (F1665) pAb.
MRCKβ (F1665) Peptide Applications :
Blocking Background :
Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues. Myotonic dystrophy kinaserelated Cdc42-binding (DMPK-like) kinases-α and β (MRCK-α, β) contain a cysteine-rich motif and a putative pleckstrin homology domain. MRCKs can phosphorylate nonmuscle Myosin light chain and influences Actin-Myosin contractility. MRCK-α can phosphorylate and activate LIM kinases downstream of Cdc42, which leads to inactivation of ADF/Cofilin and to Actin cytoskeletal reorganization. MRCK-α can also influence neurite outgrowth promoted by Cdc42 and Rac. Alternative Name :
MRCKβ; CDC42BPB; KIAA1124; MRCK beta Swiss-Prot :
Q9Y5S2 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide MRCKβ (F1665). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2382 MRCKβ (F1665) pAb.
Blocking peptide available as BS2382PP