Arrestin-C (E374) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Arrestin-C (E374) Peptide Applications :
Blocking Background :
Members of Arrestin/β-Arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters or sensory signals. Arrestin-C, also known as retinal cone Arrestin-3, X-Arrestin or cArr, is a member of the Arrestin family of proteins. It is predominantly found in the retina and pineal gland and localizes to the inner and outer segments of red-, green- and blue-cone photoreceptors and the inner plexiform regions. Two Arrestin-C isoforms exist due to alternative splicing. Isoform 1 is the mature full length protein and isoform 2 is truncated, ending with an arginine for amino acid residue 359. Arrestin-C expression is stimulated by retinoic acid. It may play a role in retina-specific signal transduction and bind to photoactivated-phosphorylated red/green opsins. In addition, Arrestin-C forms homodimers and oligomers with β-Arrestins and may regulate β-Arrestin mediated signaling. Alternative Name :
Arrestin-C; Arrestin C; ArrestinC; Cone arrestin; C-arrestin; cArr; Retinal cone arrestin-3; X-arrestin; ARR3; ARRX; CAR Swiss-Prot :
P36575 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Arrestin-C (E374). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2394 Arrestin-C (E374) pAb.
Arrestin-C (E374) Peptide Applications :
Blocking Background :
Members of Arrestin/β-Arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters or sensory signals. Arrestin-C, also known as retinal cone Arrestin-3, X-Arrestin or cArr, is a member of the Arrestin family of proteins. It is predominantly found in the retina and pineal gland and localizes to the inner and outer segments of red-, green- and blue-cone photoreceptors and the inner plexiform regions. Two Arrestin-C isoforms exist due to alternative splicing. Isoform 1 is the mature full length protein and isoform 2 is truncated, ending with an arginine for amino acid residue 359. Arrestin-C expression is stimulated by retinoic acid. It may play a role in retina-specific signal transduction and bind to photoactivated-phosphorylated red/green opsins. In addition, Arrestin-C forms homodimers and oligomers with β-Arrestins and may regulate β-Arrestin mediated signaling. Alternative Name :
Arrestin-C; Arrestin C; ArrestinC; Cone arrestin; C-arrestin; cArr; Retinal cone arrestin-3; X-arrestin; ARR3; ARRX; CAR Swiss-Prot :
P36575 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Arrestin-C (E374). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2394 Arrestin-C (E374) pAb.
Blocking peptide available as BS2394PP