WWOX (A7) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
WWOX (A7) Peptide Applications :
Blocking Background :
WWOX (WW domain containing oxidoreductase) protein is a candidate tumor suppressor consisting of two WW domains that influence protein-protein interactions, and a short chain dehydrogenase (SDR) domain, that influences sex-steroid metabolism. Modulation of the WWOX gene influences esophageal squamous cell carcinogenesis and tumorigenicity of breast cancer cell lines MDA-MB-435 and T47D. The murine homolog WOX1 localizes in the mitochondria, and contains a mitochondrial targeting sequence mapping within the SDR domain. JNK1 can physically associate with WOX1 and sequester WOX1-dependent apoptosis. Alternative Name :
Rabbit anti WWOX; EC 1.1.1.-; Fragile site FRA16D oxidoreductase; WWOX; FOR; WOX1 Swiss-Prot :
Q9NZC7 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide WWOX (A7). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2426 WWOX (A7) pAb.
WWOX (A7) Peptide Applications :
Blocking Background :
WWOX (WW domain containing oxidoreductase) protein is a candidate tumor suppressor consisting of two WW domains that influence protein-protein interactions, and a short chain dehydrogenase (SDR) domain, that influences sex-steroid metabolism. Modulation of the WWOX gene influences esophageal squamous cell carcinogenesis and tumorigenicity of breast cancer cell lines MDA-MB-435 and T47D. The murine homolog WOX1 localizes in the mitochondria, and contains a mitochondrial targeting sequence mapping within the SDR domain. JNK1 can physically associate with WOX1 and sequester WOX1-dependent apoptosis. Alternative Name :
Rabbit anti WWOX; EC 1.1.1.-; Fragile site FRA16D oxidoreductase; WWOX; FOR; WOX1 Swiss-Prot :
Q9NZC7 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide WWOX (A7). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2426 WWOX (A7) pAb.
Blocking peptide available as BS2426PP