Product Name :
TWEAK (P73) Peptide Applications :
Blocking Background :
TWEAK is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. It is widely expressed, has high constitutive expression in heart placenta, lung, muscle, kidney, pancreas, and HUVEC. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. TWEAK can induce apoptosis via multiple pathways of cell death in a cell type specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative Name :
Rabbit anti TWEAK; TNF-related weak inducer of apoptosis; TWEAK; APO3 ligand; TNFSF12; APO3L; DR3LG Swiss-Prot :
O43508 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TWEAK (P73). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2454 TWEAK (P73) pAb.
TWEAK (P73) Peptide Applications :
Blocking Background :
TWEAK is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. It is widely expressed, has high constitutive expression in heart placenta, lung, muscle, kidney, pancreas, and HUVEC. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. TWEAK can induce apoptosis via multiple pathways of cell death in a cell type specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative Name :
Rabbit anti TWEAK; TNF-related weak inducer of apoptosis; TWEAK; APO3 ligand; TNFSF12; APO3L; DR3LG Swiss-Prot :
O43508 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TWEAK (P73). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2454 TWEAK (P73) pAb.
Blocking peptide available as BS2454PP