TAF5L (E323) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
TAF5L (E323) Peptide Applications :
Blocking Background :
TFIID is a general transcription factor that initiates preinitiation complex as-sembly through direct interaction with the TATA promoter element. Functioning as a multisubunit complex consisting of a small TATA-binding polypeptide and other TBP-associated factors (TAFs), TFIID mediates promoter responses to various transcriptional activators and repressors. TAF5L (TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L), also known as PAF65B, is a 589 amino acid protein that localizes to the nucleus and contains six WD repeats. Existing as a component of the PCAF histone acetylase complex, TAF5L interacts with a number of TAFs and, via this interaction, plays a role in histone acetylation and transcription initiation. Defects in the gene encoding TAF5L, which is expressed as multiple alternatively spliced isoforms, are associated with the pathogenesis of type I diabetes. Alternative Name :
TAF 5L; PAF65 beta; PAF65B; PCAF associated factor 65 Taf5l; Taf5l protein; Swiss-Prot :
O75529 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TAF5L (E323). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2460 TAF5L (E323) pAb.
TAF5L (E323) Peptide Applications :
Blocking Background :
TFIID is a general transcription factor that initiates preinitiation complex as-sembly through direct interaction with the TATA promoter element. Functioning as a multisubunit complex consisting of a small TATA-binding polypeptide and other TBP-associated factors (TAFs), TFIID mediates promoter responses to various transcriptional activators and repressors. TAF5L (TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L), also known as PAF65B, is a 589 amino acid protein that localizes to the nucleus and contains six WD repeats. Existing as a component of the PCAF histone acetylase complex, TAF5L interacts with a number of TAFs and, via this interaction, plays a role in histone acetylation and transcription initiation. Defects in the gene encoding TAF5L, which is expressed as multiple alternatively spliced isoforms, are associated with the pathogenesis of type I diabetes. Alternative Name :
TAF 5L; PAF65 beta; PAF65B; PCAF associated factor 65 Taf5l; Taf5l protein; Swiss-Prot :
O75529 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TAF5L (E323). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2460 TAF5L (E323) pAb.
Blocking peptide available as BS2460PP