Fes (K161) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Fes (K161) Peptide Applications :
Blocking Background :
FES is a protooncogene that encodes a protein-tyrosine kinase distinct from c-Src, c-Abl and other nonreceptor tyrosine kinases. FES was originally identified as the cellular homolog of several transforming retroviral oncoproteins. FES plays a role in regulating cytoskeletal rearrangements and inside out signalling that accompany receptor ligand, cell matrix and cell-cell interaction. Genetic analysis using transgenic mouse model implicate FES in the regulation of inflammation and innate immunity. FES modulates the innate immune response of macrophages to LPS challenge, in part, by regulating the internalization and down-regulation of the TLR4 receptor complex. Alternative Name :
Proto-oncogene tyrosine-protein kinase FES/FPS; C-FES Swiss-Prot :
P07332 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Fes (K161). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2464 Fes (K161) pAb.
Fes (K161) Peptide Applications :
Blocking Background :
FES is a protooncogene that encodes a protein-tyrosine kinase distinct from c-Src, c-Abl and other nonreceptor tyrosine kinases. FES was originally identified as the cellular homolog of several transforming retroviral oncoproteins. FES plays a role in regulating cytoskeletal rearrangements and inside out signalling that accompany receptor ligand, cell matrix and cell-cell interaction. Genetic analysis using transgenic mouse model implicate FES in the regulation of inflammation and innate immunity. FES modulates the innate immune response of macrophages to LPS challenge, in part, by regulating the internalization and down-regulation of the TLR4 receptor complex. Alternative Name :
Proto-oncogene tyrosine-protein kinase FES/FPS; C-FES Swiss-Prot :
P07332 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Fes (K161). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2464 Fes (K161) pAb.
Blocking peptide available as BS2464PP