UDG (H221) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
UDG (H221) Peptide Applications :
Blocking Background :
The human UNG-gene encodes nuclear (UNG2) and mitochondrial (UNG1) forms of uracil-DNA glycosylase using differentially regulated promoters, PA and PB, and alternative splicing to produce two proteins with unique N-terminal sorting sequences. Uracil in DNA may result from deamination of cytosine which can give rise to transition mutations. Uracil-DNA glycosylase is the DNA repair enzyme responsible for the removal of uracil from DNA. This is probably a biologically important function in the prevention of mutagenesis resulting from cytosine deamination. UNG2 removes misincorporated dUMP residues. Alternative Name :
DGU; UNG1; UNG15; UNG; Uracil-DNA glycosylase ; Swiss-Prot :
P13051 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide UDG (H221). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2465 UDG (H221) pAb.
UDG (H221) Peptide Applications :
Blocking Background :
The human UNG-gene encodes nuclear (UNG2) and mitochondrial (UNG1) forms of uracil-DNA glycosylase using differentially regulated promoters, PA and PB, and alternative splicing to produce two proteins with unique N-terminal sorting sequences. Uracil in DNA may result from deamination of cytosine which can give rise to transition mutations. Uracil-DNA glycosylase is the DNA repair enzyme responsible for the removal of uracil from DNA. This is probably a biologically important function in the prevention of mutagenesis resulting from cytosine deamination. UNG2 removes misincorporated dUMP residues. Alternative Name :
DGU; UNG1; UNG15; UNG; Uracil-DNA glycosylase ; Swiss-Prot :
P13051 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide UDG (H221). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2465 UDG (H221) pAb.
Blocking peptide available as BS2465PP