ER81 (N23) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
ER81 (N23) Peptide Applications :
Blocking Background :
Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung and heart. ER81 is also moderately expressed in spleen, pancreas, colon and small intestine. During development, ER81 displays a unique expression patterns which suggests that this transcriptional factor might play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits ER81. Alternative Name :
ETV1; ER81; ETS translocation variant 1; Ets-related protein 81 Swiss-Prot :
P50549 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ER81 (N23). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2475 ER81 (N23) pAb.
ER81 (N23) Peptide Applications :
Blocking Background :
Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung and heart. ER81 is also moderately expressed in spleen, pancreas, colon and small intestine. During development, ER81 displays a unique expression patterns which suggests that this transcriptional factor might play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits ER81. Alternative Name :
ETV1; ER81; ETS translocation variant 1; Ets-related protein 81 Swiss-Prot :
P50549 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ER81 (N23). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2475 ER81 (N23) pAb.
Blocking peptide available as BS2475PP