TAF II p68 (N380) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
TAF II p68 (N380) Peptide Applications :
Blocking Background :
TAF II p68, also known as TAF15, RBP56 or TAF2N, is a member of the RNA polymerase II multiprotein complex and is present in certain TFIID subcomplexes. Expressed throughout the body, TAF II p68 is a single stranded RNA binding protein that shares homology with TLS (translocated in liposarcoma) and EWS (Ewing's sarcoma), both of which are proto-oncogenes. Fusion of TAF II p68 with certain transcription factors transforms it into an oncoprotein with oncogenic potential at the N-terminus. When, for example, TAF II p68 is fused with TEC (translocated in extraskeletal chondrosarcoma), the fusion pair acts as an oncoprotein in which TAF II p68 is the transactivation domain. Defects in the gene encoding TAF II p68 are associated with extraskeletal myxoid chondrosarcoma, a malignant soft tumor. Alternative Name :
Npl3; RBP56; RNA binding protein 56; RNA-binding protein 56; TAF; TAF(II)68; TAF15; TAF2N; TAFII68; Swiss-Prot :
Q92804 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TAF II p68 (N380). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2499 TAF II p68 (N380) pAb.
TAF II p68 (N380) Peptide Applications :
Blocking Background :
TAF II p68, also known as TAF15, RBP56 or TAF2N, is a member of the RNA polymerase II multiprotein complex and is present in certain TFIID subcomplexes. Expressed throughout the body, TAF II p68 is a single stranded RNA binding protein that shares homology with TLS (translocated in liposarcoma) and EWS (Ewing's sarcoma), both of which are proto-oncogenes. Fusion of TAF II p68 with certain transcription factors transforms it into an oncoprotein with oncogenic potential at the N-terminus. When, for example, TAF II p68 is fused with TEC (translocated in extraskeletal chondrosarcoma), the fusion pair acts as an oncoprotein in which TAF II p68 is the transactivation domain. Defects in the gene encoding TAF II p68 are associated with extraskeletal myxoid chondrosarcoma, a malignant soft tumor. Alternative Name :
Npl3; RBP56; RNA binding protein 56; RNA-binding protein 56; TAF; TAF(II)68; TAF15; TAF2N; TAFII68; Swiss-Prot :
Q92804 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TAF II p68 (N380). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2499 TAF II p68 (N380) pAb.
Blocking peptide available as BS2499PP