Product Name :
Bcl-w (G154) Peptide Applications :
Blocking Background :
Using a PCR-based strategy, an additional protein with life-promoting activity, designated Bcl-w, has been identified. The protein is highly conserved between mouse and human and is encoded by a gene located near the TCRα gene on chromosome 14. Bcl-w is expressed in myeloid cell lines but not in T and B lymphocytes, and can be found in a wide range of tissues. An alternative splicing event in exon 4 results in two transcripts. The first, Bcl-w, encodes a protein of 193 amino acids, and the second, Bcl-w/rox, encodes a protein 333 amino acids in length. The “rox” portion of Bcl-w/rox shows a striking 66% amino acid sequence identity with the Drosophila rox2 protein; however, the Bcl-w/rox transcript may be expressed at very low levels. Alternative Name :
Bcl-2-like protein 2; Bcl2-L-2; Apoptosis regulator Bcl-W; BCL2L2; BCLW; KIAA0271 Swiss-Prot :
Q92843 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Bcl-w (G154). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2532 Bcl-w (G154) pAb.
Bcl-w (G154) Peptide Applications :
Blocking Background :
Using a PCR-based strategy, an additional protein with life-promoting activity, designated Bcl-w, has been identified. The protein is highly conserved between mouse and human and is encoded by a gene located near the TCRα gene on chromosome 14. Bcl-w is expressed in myeloid cell lines but not in T and B lymphocytes, and can be found in a wide range of tissues. An alternative splicing event in exon 4 results in two transcripts. The first, Bcl-w, encodes a protein of 193 amino acids, and the second, Bcl-w/rox, encodes a protein 333 amino acids in length. The “rox” portion of Bcl-w/rox shows a striking 66% amino acid sequence identity with the Drosophila rox2 protein; however, the Bcl-w/rox transcript may be expressed at very low levels. Alternative Name :
Bcl-2-like protein 2; Bcl2-L-2; Apoptosis regulator Bcl-W; BCL2L2; BCLW; KIAA0271 Swiss-Prot :
Q92843 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Bcl-w (G154). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2532 Bcl-w (G154) pAb.
Blocking peptide available as BS2532PP