BLNK (N91) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
BLNK (N91) Peptide Applications :
Blocking Background :
B-cell linker protein (BLNK, also known as SLP65, BASH, and BCA) is a B cell adaptor that plays an important role in B cell development and in BCR-signal transduction. Since BLNK does not encode any intrinsic enzymatic activity, its function is to serve as a scaffold for assembling macromolecular complexes which includes enzymes (PLC gamma, Vav and Btk) and additional linker proteins (Grb2 and Nck) (1-3) . In addition, BLNK binds Btk and is required for activation of the transcription factor NF-κB. Tyrosine phosphorylation of BLNK by Syk provides specific docking sites for these SH2-containing effector proteins which in turn permits phosphorylation and/or activation of their respective signaling pathways. Alternative Name :
B-cell linker protein; BASH; BASH; Bca; Bca; BLNK; BLNK s; BLNK; Cytoplasmic adapter protein; Ly 57; Ly 57; Ly57; Lymphocyte antigen 57; Lymphocyte antigen 57; Lyw 57; Lyw57; Lyw57; MGC111051; SLP 65; SLP 65; SLP-65; SLP65; Swiss-Prot :
Q8WV28 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide BLNK (N91). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2547 BLNK (N91) pAb.
BLNK (N91) Peptide Applications :
Blocking Background :
B-cell linker protein (BLNK, also known as SLP65, BASH, and BCA) is a B cell adaptor that plays an important role in B cell development and in BCR-signal transduction. Since BLNK does not encode any intrinsic enzymatic activity, its function is to serve as a scaffold for assembling macromolecular complexes which includes enzymes (PLC gamma, Vav and Btk) and additional linker proteins (Grb2 and Nck) (1-3) . In addition, BLNK binds Btk and is required for activation of the transcription factor NF-κB. Tyrosine phosphorylation of BLNK by Syk provides specific docking sites for these SH2-containing effector proteins which in turn permits phosphorylation and/or activation of their respective signaling pathways. Alternative Name :
B-cell linker protein; BASH; BASH; Bca; Bca; BLNK; BLNK s; BLNK; Cytoplasmic adapter protein; Ly 57; Ly 57; Ly57; Lymphocyte antigen 57; Lymphocyte antigen 57; Lyw 57; Lyw57; Lyw57; MGC111051; SLP 65; SLP 65; SLP-65; SLP65; Swiss-Prot :
Q8WV28 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide BLNK (N91). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2547 BLNK (N91) pAb.
Blocking peptide available as BS2547PP