Product Name :
Cadherin-8 (A519) Peptide Applications :
Blocking Background :
The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including β-catenin, to regulate cadherin function. Cadherin-8 expression has been seen in mouse thymus tissue as well as in specific subdivisions of the developing central nervous system. It plays a potential role in brain morphology. Alternative Name :
Cadherin 8; CADH8; Cadherin8 Swiss-Prot :
P55286 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Cadherin-8 (A519). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2578 Cadherin-8 (A519) pAb.
Cadherin-8 (A519) Peptide Applications :
Blocking Background :
The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including β-catenin, to regulate cadherin function. Cadherin-8 expression has been seen in mouse thymus tissue as well as in specific subdivisions of the developing central nervous system. It plays a potential role in brain morphology. Alternative Name :
Cadherin 8; CADH8; Cadherin8 Swiss-Prot :
P55286 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Cadherin-8 (A519). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2578 Cadherin-8 (A519) pAb.
Blocking peptide available as BS2578PP