HM74 (T327) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
HM74 (T327) Peptide Applications :
Blocking Background :
This is a receptor for nicotinic acid. Acts as a low affinity receptor for nicotinic acid and mediate its anti-lipolytic effect through a G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Expression in humans is largely restricted to adipose tissue and spleen but there are some reports of it being expressed in lymphocytes and monocytes. In mouse is expressed in lungs, spleen, heart, skeletal muscle and adipose tissue. In rat it is expressed in adipose tissue, lung and spleen. ESTs have been isolated from adipose, blood, liver, liver/spleen, placenta, prostate, and testis libraries. Alternative Name :
GPR109B; HM74; PUMA-G; PUMAG Swiss-Prot :
P49019/Q8TDS4 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide HM74 (T327). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2605 HM74 (T327) pAb.
HM74 (T327) Peptide Applications :
Blocking Background :
This is a receptor for nicotinic acid. Acts as a low affinity receptor for nicotinic acid and mediate its anti-lipolytic effect through a G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Expression in humans is largely restricted to adipose tissue and spleen but there are some reports of it being expressed in lymphocytes and monocytes. In mouse is expressed in lungs, spleen, heart, skeletal muscle and adipose tissue. In rat it is expressed in adipose tissue, lung and spleen. ESTs have been isolated from adipose, blood, liver, liver/spleen, placenta, prostate, and testis libraries. Alternative Name :
GPR109B; HM74; PUMA-G; PUMAG Swiss-Prot :
P49019/Q8TDS4 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide HM74 (T327). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2605 HM74 (T327) pAb.
Blocking peptide available as BS2605PP