FSHR (R247) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
FSHR (R247) Peptide Applications :
Blocking Background :
Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G-protein coupled receptor. FSH binds to the receptor in a hand-clasp fashion via its α and β subunits. While the α subunit of FSH is involved in the binding of FSH to the receptor, the β subunit stabilizes this interaction. Linkage studies suggest that a missense mutation in the FSHR gene can cause reduced FSH binding affinity and lead to a condition known as hypergonadotropic ovarian dysgenesis (ODG). In males however, this mutation does not appear to have a detrimental affect on fertility. It is believed that a mutation in the FSHR gene is also associated with ovarian hyperstimulation syndrome; a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells. Alternative Name :
Follicle-stimulating hormone receptor; FSH-R; Follitropin receptor; LGR1 Swiss-Prot :
P23945 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide FSHR (R247). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2618 FSHR (R247) pAb.
FSHR (R247) Peptide Applications :
Blocking Background :
Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G-protein coupled receptor. FSH binds to the receptor in a hand-clasp fashion via its α and β subunits. While the α subunit of FSH is involved in the binding of FSH to the receptor, the β subunit stabilizes this interaction. Linkage studies suggest that a missense mutation in the FSHR gene can cause reduced FSH binding affinity and lead to a condition known as hypergonadotropic ovarian dysgenesis (ODG). In males however, this mutation does not appear to have a detrimental affect on fertility. It is believed that a mutation in the FSHR gene is also associated with ovarian hyperstimulation syndrome; a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells. Alternative Name :
Follicle-stimulating hormone receptor; FSH-R; Follitropin receptor; LGR1 Swiss-Prot :
P23945 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide FSHR (R247). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2618 FSHR (R247) pAb.
Blocking peptide available as BS2618PP