Histamine H3 Receptor (P326) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Histamine H3 Receptor (P326) Peptide Applications :
Blocking Background :
Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. The effects of histamine are mediated by a family of G protein-coupled receptors,the Histamine H1, H2, H3 and H4 Receptors. The gene encoding the human Histamine H3 Receptor is located on chromosome 20 and is expressed as six alternative splice variants in thalamus. These isoforms contain either a deletion in the second transmembrane domain or a variable deletion in the third intracellular loop. The existence of multiple H3 Receptor isoforms suggests that H3-mediated effects may be regulated through alternative splicing mechanisms.The H3 Receptor acts as an autoreceptor in the central nervous system (CNS) and modulates histamine synthesis and release. Alternative Name :
HH3R; G-protein coupled receptor 97; HRH3; GPCR97; HH3R Swiss-Prot :
Q9Y5N1 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Histamine H3 Receptor (P326). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2627 Histamine H3 Receptor (P326) pAb.
Histamine H3 Receptor (P326) Peptide Applications :
Blocking Background :
Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. The effects of histamine are mediated by a family of G protein-coupled receptors,the Histamine H1, H2, H3 and H4 Receptors. The gene encoding the human Histamine H3 Receptor is located on chromosome 20 and is expressed as six alternative splice variants in thalamus. These isoforms contain either a deletion in the second transmembrane domain or a variable deletion in the third intracellular loop. The existence of multiple H3 Receptor isoforms suggests that H3-mediated effects may be regulated through alternative splicing mechanisms.The H3 Receptor acts as an autoreceptor in the central nervous system (CNS) and modulates histamine synthesis and release. Alternative Name :
HH3R; G-protein coupled receptor 97; HRH3; GPCR97; HH3R Swiss-Prot :
Q9Y5N1 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Histamine H3 Receptor (P326). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2627 Histamine H3 Receptor (P326) pAb.
Blocking peptide available as BS2627PP