Mcl-1 (S155) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Mcl-1 (S155) Peptide Applications :
Blocking Background :
Mcl1 is an anti-apoptotic member of Bcl2 family originally isolated from the ML1 human myeloid leukemia cell line during phorbol ester-induced differentiation along the monocyte/macrophage pathway. Mcl1 localizes to the mitochondria, interacts with and antagonizes pro-apoptotic Bcl2 family members, and inhibits apoptosis by a number of cytotoxic stimuli. It is involved in programing of differentiation and concomitant maintenance of viability but not of proliferation. Isoform 1 inhibits apoptosis while isoform 2 promotes it. Expression increases early during phorbol-ester induced differentiation along the monocyte/macrophage pathway in myeloid leukemia cell lines ML1. Alternative Name :
Induced myeloid leukemia cell differentiation protein Mcl 1; Myeloid Cell Leukemia 1; BCL2 related; EAT; MCL1L; MCL1S; MGC1839; myeloid cell leukemia sequence 1; TM; MGC104264; MCL 1; Bcl 2 related protein EAT/mcl1; Mcl1/EAT; Myeloid cell leukemia se Swiss-Prot :
Q07820 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Mcl-1 (S155). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2642 Mcl-1 (S155) pAb.
Mcl-1 (S155) Peptide Applications :
Blocking Background :
Mcl1 is an anti-apoptotic member of Bcl2 family originally isolated from the ML1 human myeloid leukemia cell line during phorbol ester-induced differentiation along the monocyte/macrophage pathway. Mcl1 localizes to the mitochondria, interacts with and antagonizes pro-apoptotic Bcl2 family members, and inhibits apoptosis by a number of cytotoxic stimuli. It is involved in programing of differentiation and concomitant maintenance of viability but not of proliferation. Isoform 1 inhibits apoptosis while isoform 2 promotes it. Expression increases early during phorbol-ester induced differentiation along the monocyte/macrophage pathway in myeloid leukemia cell lines ML1. Alternative Name :
Induced myeloid leukemia cell differentiation protein Mcl 1; Myeloid Cell Leukemia 1; BCL2 related; EAT; MCL1L; MCL1S; MGC1839; myeloid cell leukemia sequence 1; TM; MGC104264; MCL 1; Bcl 2 related protein EAT/mcl1; Mcl1/EAT; Myeloid cell leukemia se Swiss-Prot :
Q07820 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Mcl-1 (S155). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2642 Mcl-1 (S155) pAb.
Blocking peptide available as BS2642PP