HLX1 (Q338) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
HLX1 (Q338) Peptide Applications :
Blocking Background :
HLX1 (homeobox protein HB24) is a 488 amino acid protein encoded by the human gene HLX1. HLX1 belongs to the H2.0 homeobox family and contains one homeobox DNA-binding domain. HLX1 is considered a diverged human homeodomain-containing protein known to be expressed in hematopoietic progenitors and activated lymphocytes. HLX1 is a transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. It is also involved in embryogenesis and hematopoiesis. Overexpression of HLX1 will cause a marked increase in activated T cells/thymocytes and interleukin-2 receptor expression. Overexpression will also impair the normal development of CD4+ T cells and will prevent the thymus from undergoing normal involution. Alternative Name :
H2.0 like homeobox 1 Drosophila; H2.0-like homeobox protein; HLX; HLX; Homeobox protein HB24; Homeobox protein HLX1; Swiss-Prot :
Q14774 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide HLX1 (Q338). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2658 HLX1 (Q338) pAb.
HLX1 (Q338) Peptide Applications :
Blocking Background :
HLX1 (homeobox protein HB24) is a 488 amino acid protein encoded by the human gene HLX1. HLX1 belongs to the H2.0 homeobox family and contains one homeobox DNA-binding domain. HLX1 is considered a diverged human homeodomain-containing protein known to be expressed in hematopoietic progenitors and activated lymphocytes. HLX1 is a transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. It is also involved in embryogenesis and hematopoiesis. Overexpression of HLX1 will cause a marked increase in activated T cells/thymocytes and interleukin-2 receptor expression. Overexpression will also impair the normal development of CD4+ T cells and will prevent the thymus from undergoing normal involution. Alternative Name :
H2.0 like homeobox 1 Drosophila; H2.0-like homeobox protein; HLX; HLX; Homeobox protein HB24; Homeobox protein HLX1; Swiss-Prot :
Q14774 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide HLX1 (Q338). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2658 HLX1 (Q338) pAb.
Blocking peptide available as BS2658PP