IRF-4 (Y294) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
IRF-4 (Y294) Peptide Applications :
Blocking Background :
Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes Alternative Name :
IRF4; IRF-4; LSIRF; MUM1; NF-EM5 Swiss-Prot :
Q15306 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide IRF-4 (Y294). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2659 IRF-4 (Y294) pAb.
IRF-4 (Y294) Peptide Applications :
Blocking Background :
Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes Alternative Name :
IRF4; IRF-4; LSIRF; MUM1; NF-EM5 Swiss-Prot :
Q15306 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide IRF-4 (Y294). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2659 IRF-4 (Y294) pAb.
Blocking peptide available as BS2659PP