OB-cadherin (K444) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
OB-cadherin (K444) Peptide Applications :
Blocking Background :
The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin β, to regulate cadherin function. Two forms of OB-cadherin (for osteoblast-cadherin, also designated cadherin-11 or OSF-4) have been identified as OBcadherin- 1 and OB-cadherin-2. Both OB-cadherins are expressed in osteoblastic cell lines and low expression is also seen in lungs, testis and brain. OB-cadherin-2 has a truncated cytoplasmic domain. Alternative Name :
CDH11; CAD11; CDHOB; OB; OB-CADHERIN; OSF-4; OSTEOBLAST-CADHERIN Swiss-Prot :
P55287 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide OB-cadherin (K444). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2684 OB-cadherin (K444) pAb.
OB-cadherin (K444) Peptide Applications :
Blocking Background :
The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin β, to regulate cadherin function. Two forms of OB-cadherin (for osteoblast-cadherin, also designated cadherin-11 or OSF-4) have been identified as OBcadherin- 1 and OB-cadherin-2. Both OB-cadherins are expressed in osteoblastic cell lines and low expression is also seen in lungs, testis and brain. OB-cadherin-2 has a truncated cytoplasmic domain. Alternative Name :
CDH11; CAD11; CDHOB; OB; OB-CADHERIN; OSF-4; OSTEOBLAST-CADHERIN Swiss-Prot :
P55287 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide OB-cadherin (K444). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2684 OB-cadherin (K444) pAb.
Blocking peptide available as BS2684PP