mAChR M1 (R336) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
mAChR M1 (R336) Peptide Applications :
Blocking Background :
The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties. The amino acid sequence of each mAChR subtype reflects a structure that is characteristic of G-protein coupled receptors, consisting of seven highly conserved transmembrane segments and a large intracellular region unique to each subtype, which constitutes the effector-coupling domain. Alternative Name :
CHRM1 ; ACM1 ; Muscarinic acetylcholine receptor M1 Swiss-Prot :
P11229 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide mAChR M1 (R336). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2708 mAChR M1 (R336) pAb.
mAChR M1 (R336) Peptide Applications :
Blocking Background :
The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties. The amino acid sequence of each mAChR subtype reflects a structure that is characteristic of G-protein coupled receptors, consisting of seven highly conserved transmembrane segments and a large intracellular region unique to each subtype, which constitutes the effector-coupling domain. Alternative Name :
CHRM1 ; ACM1 ; Muscarinic acetylcholine receptor M1 Swiss-Prot :
P11229 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide mAChR M1 (R336). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2708 mAChR M1 (R336) pAb.
Blocking peptide available as BS2708PP