Product Name :
mGluR-5 (K56) Peptide Applications :
Blocking Background :
The mGluR proteins (metabotropic glutamate receptors) are members of the G protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR-1 and mGluR-5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-3, which may interact with GRASP, acts as a receptor for glutamate. Alternative Name :
mGluR5; mGluR5; mGluR5; GPRC1E; MGLUR5 Swiss-Prot :
P41594 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide mGluR-5 (K56). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2732 mGluR-5 (K56) pAb.
mGluR-5 (K56) Peptide Applications :
Blocking Background :
The mGluR proteins (metabotropic glutamate receptors) are members of the G protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR-1 and mGluR-5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-3, which may interact with GRASP, acts as a receptor for glutamate. Alternative Name :
mGluR5; mGluR5; mGluR5; GPRC1E; MGLUR5 Swiss-Prot :
P41594 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide mGluR-5 (K56). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2732 mGluR-5 (K56) pAb.
Blocking peptide available as BS2732PP