Histamine H1 Receptor (K179) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Histamine H1 Receptor (K179) Peptide Applications :
Blocking Background :
Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. The effects of histamine are mediated by a family of G protein-coupled receptors, the Histamine H1, H2, H3 and H4 Receptors. The gene encoding the human Histamine H1 Receptor maps to chromosome 3p25 and is expressed in highest abundance in placenta, with lower levels in lung, skeletal muscle, kidney and brain. The murine Histamine H2 Receptor gene maps to chromosome 13 and is highly expressed in stomach with moderate expression in brain and heart. The gene encoding the human Histamine H3 Receptor is located on chromosome 20 and is expressed as six alternative splice variants in thalamus. The human Histamine H4 Receptor gene maps to chromosome 18q11 and is expressed most abundantly in bone marrow and spleen in addition to peripheral blood leukocytes, thymus, small intestine and colon. Alternative Name :
Histamine H1 receptor; H1R; HH1R; HRH1 Swiss-Prot :
P35367 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Histamine H1 Receptor (K179). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2733 Histamine H1 Receptor (K179) pAb.
Histamine H1 Receptor (K179) Peptide Applications :
Blocking Background :
Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. The effects of histamine are mediated by a family of G protein-coupled receptors, the Histamine H1, H2, H3 and H4 Receptors. The gene encoding the human Histamine H1 Receptor maps to chromosome 3p25 and is expressed in highest abundance in placenta, with lower levels in lung, skeletal muscle, kidney and brain. The murine Histamine H2 Receptor gene maps to chromosome 13 and is highly expressed in stomach with moderate expression in brain and heart. The gene encoding the human Histamine H3 Receptor is located on chromosome 20 and is expressed as six alternative splice variants in thalamus. The human Histamine H4 Receptor gene maps to chromosome 18q11 and is expressed most abundantly in bone marrow and spleen in addition to peripheral blood leukocytes, thymus, small intestine and colon. Alternative Name :
Histamine H1 receptor; H1R; HH1R; HRH1 Swiss-Prot :
P35367 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Histamine H1 Receptor (K179). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2733 Histamine H1 Receptor (K179) pAb.
Blocking peptide available as BS2733PP