NK-3R (P434) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
NK-3R (P434) Peptide Applications :
Blocking Background :
Substance P (SP) and neurokinin-A (NK-A) are members of the tachykinins, and they function as modulators of the immune and hematopoietic systems. The tachykinins interact with each of three cloned neurokinin (NK) receptors (NK-1R, NK-2R, NK-3R), with SP and NK-A exhibiting binding preferences for NK-1R and NK-2R, respectively. NK-4R shares close homology with NK-3R, and both have nearly identical pharmacologicl properties. In the normal ileum and colon, NK-1R and NK-2R are localized to smooth muscle cells of the muscularis mucosae and propria and to a few inflammatory cells of the lamina propria. NK-1R expression is also found in the muscular wall of submucosal blood vessels, enteric neurons and, to a lesser degree, in surface epithelial cells. NK-3R is found in the spinal cord in both lamina X and lamina II. Alternative Name :
TACR3; MGC148060; MGC148061; NK-3R; NK3R; NKR; TAC3R; TAC3RL Swiss-Prot :
P29371 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide NK-3R (P434). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2736 NK-3R (P434) pAb.
NK-3R (P434) Peptide Applications :
Blocking Background :
Substance P (SP) and neurokinin-A (NK-A) are members of the tachykinins, and they function as modulators of the immune and hematopoietic systems. The tachykinins interact with each of three cloned neurokinin (NK) receptors (NK-1R, NK-2R, NK-3R), with SP and NK-A exhibiting binding preferences for NK-1R and NK-2R, respectively. NK-4R shares close homology with NK-3R, and both have nearly identical pharmacologicl properties. In the normal ileum and colon, NK-1R and NK-2R are localized to smooth muscle cells of the muscularis mucosae and propria and to a few inflammatory cells of the lamina propria. NK-1R expression is also found in the muscular wall of submucosal blood vessels, enteric neurons and, to a lesser degree, in surface epithelial cells. NK-3R is found in the spinal cord in both lamina X and lamina II. Alternative Name :
TACR3; MGC148060; MGC148061; NK-3R; NK3R; NKR; TAC3R; TAC3RL Swiss-Prot :
P29371 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide NK-3R (P434). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2736 NK-3R (P434) pAb.
Blocking peptide available as BS2736PP