Product Name :
NPY5-R (M264) Peptide Applications :
Blocking Background :
Pancreatic polypeptide (PP), neuropeptide Y (NPY), and peptide YY (PYY) are related 36-amino acid hormones. A number of structurally related receptors for these peptides have been isolated, NPY1-R, NPY2-R, NPY3-R, NPY4-R,NPY5-R, and NPY6-R. NPY4-R is expressed in several human tissues, including brain, coronary artery, and ileum. NPY4-R maps to human chromosome 10q11.2-q21.2. NPY-5R, isolated from rat hypothalamus, encodes a 456-amino acid protein with less than 35% overall identity to known Y-type receptors. The human NPY-5R sequence is nearly identical to, but in the opposite orientation from, that of the human NPY-1R sequence. NPY5-R localizes to the paraventricular hypothalamic nucleus, the lateral hypothalamus, and other locations consistent with a role in the control of feeding behavior. The gene which encodes NPY-5R maps to human chromosome 4q31-32. NPY-6R is abundantly expressed in human heart and skeletal muscle and the gene which encodes NPY-6R maps to human chromosome 5q31. Alternative Name :
NPY5-R; NPY-Y5 receptor; Y5 receptor; NPYY5; NPY5R; NPYR5 Swiss-Prot :
Q15761 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide NPY5-R (M264). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2819 NPY5-R (M264) pAb.
NPY5-R (M264) Peptide Applications :
Blocking Background :
Pancreatic polypeptide (PP), neuropeptide Y (NPY), and peptide YY (PYY) are related 36-amino acid hormones. A number of structurally related receptors for these peptides have been isolated, NPY1-R, NPY2-R, NPY3-R, NPY4-R,NPY5-R, and NPY6-R. NPY4-R is expressed in several human tissues, including brain, coronary artery, and ileum. NPY4-R maps to human chromosome 10q11.2-q21.2. NPY-5R, isolated from rat hypothalamus, encodes a 456-amino acid protein with less than 35% overall identity to known Y-type receptors. The human NPY-5R sequence is nearly identical to, but in the opposite orientation from, that of the human NPY-1R sequence. NPY5-R localizes to the paraventricular hypothalamic nucleus, the lateral hypothalamus, and other locations consistent with a role in the control of feeding behavior. The gene which encodes NPY-5R maps to human chromosome 4q31-32. NPY-6R is abundantly expressed in human heart and skeletal muscle and the gene which encodes NPY-6R maps to human chromosome 5q31. Alternative Name :
NPY5-R; NPY-Y5 receptor; Y5 receptor; NPYY5; NPY5R; NPYR5 Swiss-Prot :
Q15761 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide NPY5-R (M264). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2819 NPY5-R (M264) pAb.
Blocking peptide available as BS2819PP