Product Name :
RUNX-2 (N278) Peptide Applications :
Blocking Background :
RUNX2 (Runt-related transcription Factor) is a transcription factor that binds to its canonical consensus sequence 5’- PYGPYGGT-3’ in a number of promoters and enhancers. They include LCK, T-cell receptor enhancers, and various bone related genes such as osteocalcin, osteopontin, and bone sialoprotein. As a result of this, RUNX2 is involved in osteoblastic differentiation and skeletal morphogenesis. RUNX2 contains a proline/serine/ threonine-rich region at its C-terminus that has shown to be critical for its transcriptional activity. Alternative Name :
CASP3; APOPAIN; CASP-3; CPP-32; CPP32; CPP32B; EC 3.4.22.-; SCA-1; YAMA; Swiss-Prot :
Q13950 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide RUNX-2 (N278). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2831 RUNX-2 (N278) pAb.
RUNX-2 (N278) Peptide Applications :
Blocking Background :
RUNX2 (Runt-related transcription Factor) is a transcription factor that binds to its canonical consensus sequence 5’- PYGPYGGT-3’ in a number of promoters and enhancers. They include LCK, T-cell receptor enhancers, and various bone related genes such as osteocalcin, osteopontin, and bone sialoprotein. As a result of this, RUNX2 is involved in osteoblastic differentiation and skeletal morphogenesis. RUNX2 contains a proline/serine/ threonine-rich region at its C-terminus that has shown to be critical for its transcriptional activity. Alternative Name :
CASP3; APOPAIN; CASP-3; CPP-32; CPP32; CPP32B; EC 3.4.22.-; SCA-1; YAMA; Swiss-Prot :
Q13950 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide RUNX-2 (N278). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2831 RUNX-2 (N278) pAb.
Blocking peptide available as BS2831PP