PEDF (T307) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
PEDF (T307) Peptide Applications :
Blocking Background :
Pigment epithelium derived factor, originally identified in conditioned medium of cultured human fetal retinal pigment epithelial (RPE) cells, is a neurotrophic protein that induces extensive neuronal differentiation in human Y79 retinoblastoma cells, a neoplastic counterpart of normal retinoblasts. It has been suggested that PEDF is synthesized by RPE cells and secreted into the retina interphotoreceptor matrix where it may influence development/differentiation of the neural retina. PEDF is a potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. The PEDF gene is a member of the serpin gene family. Serpins are a group of serine protease inhibitors, some of which have also been reported to exhibit neurotrophic activity. Alternative Name :
Cell proliferation-inducing gene 35 protein; EPC 1; EPC-1; EPC1; PEDF; PEDF; PIG 35; PIG35; Pigment epithelium derived factor; Pigment epithelium-derived factor; Proliferation inducing protein 35; Serpin F1; Serpin peptidase inhibitor clade F member 1; SERPINF 1; Serpinf1; Swiss-Prot :
P36955 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PEDF (T307). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2842 PEDF (T307) pAb.
PEDF (T307) Peptide Applications :
Blocking Background :
Pigment epithelium derived factor, originally identified in conditioned medium of cultured human fetal retinal pigment epithelial (RPE) cells, is a neurotrophic protein that induces extensive neuronal differentiation in human Y79 retinoblastoma cells, a neoplastic counterpart of normal retinoblasts. It has been suggested that PEDF is synthesized by RPE cells and secreted into the retina interphotoreceptor matrix where it may influence development/differentiation of the neural retina. PEDF is a potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. The PEDF gene is a member of the serpin gene family. Serpins are a group of serine protease inhibitors, some of which have also been reported to exhibit neurotrophic activity. Alternative Name :
Cell proliferation-inducing gene 35 protein; EPC 1; EPC-1; EPC1; PEDF; PEDF; PIG 35; PIG35; Pigment epithelium derived factor; Pigment epithelium-derived factor; Proliferation inducing protein 35; Serpin F1; Serpin peptidase inhibitor clade F member 1; SERPINF 1; Serpinf1; Swiss-Prot :
P36955 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PEDF (T307). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2842 PEDF (T307) pAb.
Blocking peptide available as BS2842PP