Product Name :
AChRα3 (L139) Peptide Applications :
Blocking Background :
The nicotinic acetylcholine receptor (nAChR) is a ligand gated ion channel that mediates neurotransmission at the neuromuscular junction, autonomic ganglia and at some sites in the central nervous system. Distinct nAChR subtypes exist that can be stimulated by the neurotransmitter acetylcholine, the natural product nicotine, or by synthetic compounds. After binding acetylcholine, Nicotinic Acetylcholine Receptor alpha 3 responds by an extensive change in conformation that affects all subunits and leads to opening of an ion conducting channel across the plasma membrane. Alternative Name :
Neuronal acetylcholine receptor subunit alpha-3; NACHRA3; CHRNA3 Swiss-Prot :
P32297 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide AChRα3 (L139). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2851 AChRα3 (L139) pAb.
AChRα3 (L139) Peptide Applications :
Blocking Background :
The nicotinic acetylcholine receptor (nAChR) is a ligand gated ion channel that mediates neurotransmission at the neuromuscular junction, autonomic ganglia and at some sites in the central nervous system. Distinct nAChR subtypes exist that can be stimulated by the neurotransmitter acetylcholine, the natural product nicotine, or by synthetic compounds. After binding acetylcholine, Nicotinic Acetylcholine Receptor alpha 3 responds by an extensive change in conformation that affects all subunits and leads to opening of an ion conducting channel across the plasma membrane. Alternative Name :
Neuronal acetylcholine receptor subunit alpha-3; NACHRA3; CHRNA3 Swiss-Prot :
P32297 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide AChRα3 (L139). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2851 AChRα3 (L139) pAb.
Blocking peptide available as BS2851PP