Product Name :
BRCA2 (N60) Peptide Applications :
Blocking Background :
BRCA 2 is localized to chromosome 13q12 - q13. Loss of heterozygosity of 13q is observed in 25% of sporadic breast tumors, which indicates that BRCA 2 might be a tumor suppressor gene. BRCA 2 confers only a low ovarian cancer risk. Reportedly, in MCF-10F (normal breast epithelial cell line) and MCF-7 (breast cancer cell line) cells the expression of BRCA 2 RNA lowers in G0 and early G1 phases then gets up-regulated at the G1 / S phase junction. Alternative Name :
Fanconi anemia group D1 protein; Breast cancer type 2 susceptibility protein; BRCA2; FACD; FANCD1 Swiss-Prot :
P51587 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide BRCA2 (N60). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2864 BRCA2 (N60) pAb.

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Blocking peptide available as BS2864PP