SOCS-2 (E67) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
SOCS-2 (E67) Peptide Applications :
Blocking Background :
SOCS2 is capable of inhibiting cytokine signalling by interleukin-6 (IL-6) and growth hormone. SOCS2 interacts with the phosphorylated insulin-like growth factor (IGF-I) receptor, where it may play a regulatory role in cellular growth, differentiation, and inhibition of apoptosis via the Ras and PI3K signalling pathways. In humans, SOCS2 mRNA is expressed widely in both foetal and adult tissues, including foetal kidney and adult heart, skeletal muscle, pancreas, and liver. In rats, SOCS2 mRNA exhibits high levels of expression in liver and heart, and in the mouse nervous system, SOCS2 is expressed exclusively by neurons, where it is switched on developmentally in concordance with neuronal differentiation. Alternative Name :
Suppressor of cytokine signaling 2; SOCS-2; Cytokine-inducible SH2 protein 2; Short name=CIS-2; STAT-induced STAT inhibitor 2; Short name=SSI-2; CIS2; SSI2; STATI2; SOCS2 Swiss-Prot :
O14508 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide SOCS-2 (E67). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2914 SOCS-2 (E67) pAb.
SOCS-2 (E67) Peptide Applications :
Blocking Background :
SOCS2 is capable of inhibiting cytokine signalling by interleukin-6 (IL-6) and growth hormone. SOCS2 interacts with the phosphorylated insulin-like growth factor (IGF-I) receptor, where it may play a regulatory role in cellular growth, differentiation, and inhibition of apoptosis via the Ras and PI3K signalling pathways. In humans, SOCS2 mRNA is expressed widely in both foetal and adult tissues, including foetal kidney and adult heart, skeletal muscle, pancreas, and liver. In rats, SOCS2 mRNA exhibits high levels of expression in liver and heart, and in the mouse nervous system, SOCS2 is expressed exclusively by neurons, where it is switched on developmentally in concordance with neuronal differentiation. Alternative Name :
Suppressor of cytokine signaling 2; SOCS-2; Cytokine-inducible SH2 protein 2; Short name=CIS-2; STAT-induced STAT inhibitor 2; Short name=SSI-2; CIS2; SSI2; STATI2; SOCS2 Swiss-Prot :
O14508 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide SOCS-2 (E67). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2914 SOCS-2 (E67) pAb.
Blocking peptide available as BS2914PP