Product Name :
Synphilin-1 (R846) Peptide Applications :
Blocking Background :
Synphilin-1 (α-synuclein interacting protein, SNCAIP) is a 919 amino acid protein that associates with α synuclein and promotes the formation of cytosolic inclusions in neuronal cells. The synuclein family members, including α-synuclein and β-synuclein, are predominantly expressed in the brain, where they influence synaptic regulation and neuronal plasticity. Synphilin-1 contains modular protein domains, such as ankyrin-like repeats and a coiled-coil domain.While both α-synuclein and synphilin-1 are coexpressed in Lewy bodies of patients with Parkinson’s disease, only mutations in the gene for α-synuclein have been determined to confer pathogenicity. Alternative Name :
Synphilin-1; Sph1; Alpha-synuclein-interacting protein; SNCAIP Swiss-Prot :
Q9Y6H5 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Synphilin-1 (R846). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2939 Synphilin-1 (R846) pAb.
Synphilin-1 (R846) Peptide Applications :
Blocking Background :
Synphilin-1 (α-synuclein interacting protein, SNCAIP) is a 919 amino acid protein that associates with α synuclein and promotes the formation of cytosolic inclusions in neuronal cells. The synuclein family members, including α-synuclein and β-synuclein, are predominantly expressed in the brain, where they influence synaptic regulation and neuronal plasticity. Synphilin-1 contains modular protein domains, such as ankyrin-like repeats and a coiled-coil domain.While both α-synuclein and synphilin-1 are coexpressed in Lewy bodies of patients with Parkinson’s disease, only mutations in the gene for α-synuclein have been determined to confer pathogenicity. Alternative Name :
Synphilin-1; Sph1; Alpha-synuclein-interacting protein; SNCAIP Swiss-Prot :
Q9Y6H5 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Synphilin-1 (R846). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2939 Synphilin-1 (R846) pAb.
Blocking peptide available as BS2939PP