Product Name :
THP (V378) Peptide Applications :
Blocking Background :
Tamm-Horsfall glycoprotein (also referred to as uromodulin or THP) is the most abundant protein found in normal urine. THP is expressed on the luminal surface of the membrane with the glycosyl phosphatidylinositol (GPI) anchor and excreted in urine at a rate of 50-100 mg per day. THP, uropontin and nephrocalcin are the three known urinary glycoproteins that affect the formation of calcium-containing kidney stones. THP is synthesized by kidney epithelial cells and is believed to play important and diverse roles in the urinary system,including renal water balance, immunosuppression, urinary stone formation and inhibition of bacterial adhesion. THP is nontoxic and blocks early events required for normal T cell proliferation in vitro. Alternative Name :
Uromodulin; Tamm-Horsfall urinary glycoprotein; THP; UMOD Swiss-Prot :
P07911 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide THP (V378). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2944 THP (V378) pAb.
THP (V378) Peptide Applications :
Blocking Background :
Tamm-Horsfall glycoprotein (also referred to as uromodulin or THP) is the most abundant protein found in normal urine. THP is expressed on the luminal surface of the membrane with the glycosyl phosphatidylinositol (GPI) anchor and excreted in urine at a rate of 50-100 mg per day. THP, uropontin and nephrocalcin are the three known urinary glycoproteins that affect the formation of calcium-containing kidney stones. THP is synthesized by kidney epithelial cells and is believed to play important and diverse roles in the urinary system,including renal water balance, immunosuppression, urinary stone formation and inhibition of bacterial adhesion. THP is nontoxic and blocks early events required for normal T cell proliferation in vitro. Alternative Name :
Uromodulin; Tamm-Horsfall urinary glycoprotein; THP; UMOD Swiss-Prot :
P07911 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide THP (V378). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2944 THP (V378) pAb.
Blocking peptide available as BS2944PP