NQO1 (F252) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
NQO1 (F252) Peptide Applications :
Blocking Background :
NAD(P)H:quinone oxidoreductase 1 (NQO1) is a flavoprotein that catalyzes the two-electron reduction of quinones and their derivatives. This enzyme protects cells against redox cycling and oxidative stress. The expression of NQO1 is increased in liver, colon and breast tumors and non-small cell lung cancer (NSCLC) compared with the normal tissues. Moreover, expression levels are also elevated in developing tumors, suggesting a role for NQ01 in the prevention of tumor development. Studies on NQO1 knockout mice suggest that the lack of NQO1 enzymatic activity changes intracellular redox states resulting in a reduction in apoptosis, which in turns leads to myeloid hyperplasia of bone marrow. Alternative Name :
DHQU; DIA4; DTD; NMOR1; NMORI; QR1 Swiss-Prot :
P15559 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide NQO1 (F252). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2945 NQO1 (F252) pAb.
NQO1 (F252) Peptide Applications :
Blocking Background :
NAD(P)H:quinone oxidoreductase 1 (NQO1) is a flavoprotein that catalyzes the two-electron reduction of quinones and their derivatives. This enzyme protects cells against redox cycling and oxidative stress. The expression of NQO1 is increased in liver, colon and breast tumors and non-small cell lung cancer (NSCLC) compared with the normal tissues. Moreover, expression levels are also elevated in developing tumors, suggesting a role for NQ01 in the prevention of tumor development. Studies on NQO1 knockout mice suggest that the lack of NQO1 enzymatic activity changes intracellular redox states resulting in a reduction in apoptosis, which in turns leads to myeloid hyperplasia of bone marrow. Alternative Name :
DHQU; DIA4; DTD; NMOR1; NMORI; QR1 Swiss-Prot :
P15559 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide NQO1 (F252). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2945 NQO1 (F252) pAb.
Blocking peptide available as BS2945PP