Product Name :
MARCKS (K152) Peptide Applications :
Blocking Background :
Myristoylated alanine-rich protein kinase C substrate (MARCKS), also designated 80K or 80K-L, has been identified as a major cellular substrate for protein kinase C. Human MARCKS is a 332 amino acid protein with a calculated molecular weight of 31.534 kDa; however, it has been shown to run at 80-87 kDa on Western blot. The plasma membrane bound protein dissociates from the membrane upon phosphorylation by various PKC isoforms. In NIH/3T3 fibroblasts, PKC α and PKC ε, but not PKC δ, are responsible for MARCKS phosphorylation. MARCKS has been found to bind calmodulin, Actin and Synapsin and is a filamentous (F) Actin crosslinking protein. Alternative Name :
Rabbit Anti MARCKS; MARCKS; ACAMP-81; MARCKS; MACS Swiss-Prot :
P29966 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide MARCKS (K152). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2982 MARCKS (K152) pAb.
MARCKS (K152) Peptide Applications :
Blocking Background :
Myristoylated alanine-rich protein kinase C substrate (MARCKS), also designated 80K or 80K-L, has been identified as a major cellular substrate for protein kinase C. Human MARCKS is a 332 amino acid protein with a calculated molecular weight of 31.534 kDa; however, it has been shown to run at 80-87 kDa on Western blot. The plasma membrane bound protein dissociates from the membrane upon phosphorylation by various PKC isoforms. In NIH/3T3 fibroblasts, PKC α and PKC ε, but not PKC δ, are responsible for MARCKS phosphorylation. MARCKS has been found to bind calmodulin, Actin and Synapsin and is a filamentous (F) Actin crosslinking protein. Alternative Name :
Rabbit Anti MARCKS; MARCKS; ACAMP-81; MARCKS; MACS Swiss-Prot :
P29966 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide MARCKS (K152). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2982 MARCKS (K152) pAb.
Blocking peptide available as BS2982PP