HNF4α (K307) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
HNF4α (K307) Peptide Applications :
Blocking Background :
Hepatocyte nuclear factor 4α (HNF4α) is a transcription factor that belongs to the steroid hormone receptor superfamily and is enriched in liver. HNF4α, in association with PGC-1α, activates gluconeogenic genes such as phosphoenolpyruvate carboxykinase and glucose-6-phosphatase genes in fasted livers. Conditional knockout of the HNF4α gene in the mouse liver destroys lipid homeostasis and leads to lipid accumulation in the liver and a reduction of serum cholesterol and triglyceride levels. Mutations in HNF4α have been linked to maturity-onset diabetes of the young (MODY). Alternative Name :
HNF 4 alpha; HNF 4; HNF-4-alpha; HNF4; HNF4A; HNF4A; HNF4a7; HNF4a8; HNF4a9; Hnf4alpha; MODY 1; MODY; MODY1; NR2A1; NR2A21; Swiss-Prot :
P41235 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide HNF4α (K307). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2983 HNF4α (K307) pAb.
HNF4α (K307) Peptide Applications :
Blocking Background :
Hepatocyte nuclear factor 4α (HNF4α) is a transcription factor that belongs to the steroid hormone receptor superfamily and is enriched in liver. HNF4α, in association with PGC-1α, activates gluconeogenic genes such as phosphoenolpyruvate carboxykinase and glucose-6-phosphatase genes in fasted livers. Conditional knockout of the HNF4α gene in the mouse liver destroys lipid homeostasis and leads to lipid accumulation in the liver and a reduction of serum cholesterol and triglyceride levels. Mutations in HNF4α have been linked to maturity-onset diabetes of the young (MODY). Alternative Name :
HNF 4 alpha; HNF 4; HNF-4-alpha; HNF4; HNF4A; HNF4A; HNF4a7; HNF4a8; HNF4a9; Hnf4alpha; MODY 1; MODY; MODY1; NR2A1; NR2A21; Swiss-Prot :
P41235 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide HNF4α (K307). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2983 HNF4α (K307) pAb.
Blocking peptide available as BS2983PP