Histone H2A.X (S130) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Histone H2A.X (S130) Peptide Applications :
Blocking Background :
H2A.X is a member of the histone H2A family, 1 of 5 families of histone proteins involved in nucleosomal organization of chromatin. H2A.X is synthesised in G1 as well as S phase and is known to be important for recombination between immunoglobulin switch regions. A very early step in the response of mammalian cells to DNA double-strand breaks is the phosphorylation of histone H2A.X at serine 139 at the sites of DNA damage. There is a predicted acetylation at residue 1 and ubiquitination at reside 119. Phosphorylated H2A.X promotes DNA repair and maintains genomic stability. Alternative Name :
Histone H2AX; H2a/x; Histone H2A.X; H2AFX; H2AX; Swiss-Prot :
P16104 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Histone H2A.X (S130). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2984 Histone H2A.X (S130) pAb.
Histone H2A.X (S130) Peptide Applications :
Blocking Background :
H2A.X is a member of the histone H2A family, 1 of 5 families of histone proteins involved in nucleosomal organization of chromatin. H2A.X is synthesised in G1 as well as S phase and is known to be important for recombination between immunoglobulin switch regions. A very early step in the response of mammalian cells to DNA double-strand breaks is the phosphorylation of histone H2A.X at serine 139 at the sites of DNA damage. There is a predicted acetylation at residue 1 and ubiquitination at reside 119. Phosphorylated H2A.X promotes DNA repair and maintains genomic stability. Alternative Name :
Histone H2AX; H2a/x; Histone H2A.X; H2AFX; H2AX; Swiss-Prot :
P16104 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Histone H2A.X (S130). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2984 Histone H2A.X (S130) pAb.
Blocking peptide available as BS2984PP