Insulin Receptor (Y1355) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Insulin Receptor (Y1355) Peptide Applications :
Blocking Background :
The insulin receptor (IR) is a heterodimeric protein complex that has an intracellular β subunit and an extracellular α subunit, which is disulfide- linked to a transmembrane segment. The insulin ligand binds to the IR and initiates molecular signaling pathways that promote glucose uptake in cells and glycogen synthesis. Insulin binding to IR induces phosphorylation of intracellular tyrosine kinase domains and recruitment of multiple SH2 and SH3 domain-containing intracellular proteins that serve as signaling intermediates for pleiotropic effects of insulin. Alternative Name :
CD 220; CD220; CD220 antigen; HHF 5; HHF5; human insulin receptor; INSR; INSR; Insulin receptor subunit beta; IR 1; IR; IR-1; IR1; Swiss-Prot :
P06213 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Insulin Receptor (Y1355). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2985 Insulin Receptor (Y1355) pAb.
Insulin Receptor (Y1355) Peptide Applications :
Blocking Background :
The insulin receptor (IR) is a heterodimeric protein complex that has an intracellular β subunit and an extracellular α subunit, which is disulfide- linked to a transmembrane segment. The insulin ligand binds to the IR and initiates molecular signaling pathways that promote glucose uptake in cells and glycogen synthesis. Insulin binding to IR induces phosphorylation of intracellular tyrosine kinase domains and recruitment of multiple SH2 and SH3 domain-containing intracellular proteins that serve as signaling intermediates for pleiotropic effects of insulin. Alternative Name :
CD 220; CD220; CD220 antigen; HHF 5; HHF5; human insulin receptor; INSR; INSR; Insulin receptor subunit beta; IR 1; IR; IR-1; IR1; Swiss-Prot :
P06213 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Insulin Receptor (Y1355). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2985 Insulin Receptor (Y1355) pAb.
Blocking peptide available as BS2985PP