Product Name :
TEBP (K107) Peptide Applications :
Blocking Background :
TTF-1 (Thyroid transcription factor-1, BCH, BHC, NK-2, Nkx2.1, Nkx2A, TEBP, TTF1) is a member of the Nkx2 family of homeodomain-containing transcription factors and regulates the transcriptional activity of thyroid-specific genes. TTF-1 is a 38 kDa protein that influences organogenisis and the maintenance of the differentiated phenotypes of various tissues including thyroid, lung and brain. TTF-1, which is present in the epithelium of the lung, regulates transcription of the surfactant proteins (SP) A, B, and C and is essential for lung morphogenesis. In the thyroid, TTF-1 elevates the expression of thyroid specific markers, thyroglobulin, thyroperoxidase and thyrotropin receptors. TTF-1 interacts with SRC-1 and CBP in vitro. Alternative Name :
TITF1; BCH; BHC; NK-2; NKX2-1; NKX2.1; NKX2A; TEBP; TTF-1; TTF1 Swiss-Prot :
Q15185 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TEBP (K107). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2986 TEBP (K107) pAb.
TEBP (K107) Peptide Applications :
Blocking Background :
TTF-1 (Thyroid transcription factor-1, BCH, BHC, NK-2, Nkx2.1, Nkx2A, TEBP, TTF1) is a member of the Nkx2 family of homeodomain-containing transcription factors and regulates the transcriptional activity of thyroid-specific genes. TTF-1 is a 38 kDa protein that influences organogenisis and the maintenance of the differentiated phenotypes of various tissues including thyroid, lung and brain. TTF-1, which is present in the epithelium of the lung, regulates transcription of the surfactant proteins (SP) A, B, and C and is essential for lung morphogenesis. In the thyroid, TTF-1 elevates the expression of thyroid specific markers, thyroglobulin, thyroperoxidase and thyrotropin receptors. TTF-1 interacts with SRC-1 and CBP in vitro. Alternative Name :
TITF1; BCH; BHC; NK-2; NKX2-1; NKX2.1; NKX2A; TEBP; TTF-1; TTF1 Swiss-Prot :
Q15185 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TEBP (K107). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2986 TEBP (K107) pAb.
Blocking peptide available as BS2986PP