MARK1/2/3/4 (N211) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
MARK1/2/3/4 (N211) Peptide Applications :
Blocking Background :
MARK1 (MAP/microtubule affinity-regulating kinase 1) belongs to the MARK family of serine/threonine kinases. MARK family protein kinases phosphorylate microtubule-associated proteins and may play a role in cytoskeletal stability. MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1 called MARK2. MARK3 was originally identified as a marker that was induced by treatment with DNA damaging agents, and loss of MARK3 was found with carcinogenesis in the pancreas. MARK4 contains an N terminal serine/threonine kinase domain, a central ubiquitin associated domain, and a C terminal KA1 associated kinase domain. RT PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells. Alternative Name :
MARK1; EC 2.7.11.1; KIAA1477; MARK; MGC126512; MGC126513 Swiss-Prot :
Q9P0L2/Q7KZI7/P27448/Q96L34 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide MARK1/2/3/4 (N211). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3001 MARK1/2/3/4 (N211) pAb.
MARK1/2/3/4 (N211) Peptide Applications :
Blocking Background :
MARK1 (MAP/microtubule affinity-regulating kinase 1) belongs to the MARK family of serine/threonine kinases. MARK family protein kinases phosphorylate microtubule-associated proteins and may play a role in cytoskeletal stability. MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1 called MARK2. MARK3 was originally identified as a marker that was induced by treatment with DNA damaging agents, and loss of MARK3 was found with carcinogenesis in the pancreas. MARK4 contains an N terminal serine/threonine kinase domain, a central ubiquitin associated domain, and a C terminal KA1 associated kinase domain. RT PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells. Alternative Name :
MARK1; EC 2.7.11.1; KIAA1477; MARK; MGC126512; MGC126513 Swiss-Prot :
Q9P0L2/Q7KZI7/P27448/Q96L34 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide MARK1/2/3/4 (N211). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3001 MARK1/2/3/4 (N211) pAb.
Blocking peptide available as BS3001PP