TPX2 (Q330) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
TPX2 (Q330) Peptide Applications :
Blocking Background :
TPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 for the chromatin-induced microbutule assembly during M phase. Aurora-A kinase associates with TPX2 at the spindle apparatus and may regulate TPX2 via phosphorylation during the spindle assembly. TPX2 appears to play a structural role in spindle formation. TPX2 activates Eg2 in a microtubuledependent manner by stimulating the phosphorylation and kinase activity of Eg2. TPX2 is inactivated by binding to importin α, a nuclear import factor. Finally, the suppression of TPX2 with RNA interference causes defects in microtubule organization during mitosis. Alternative Name :
TPX2; C20ORF1; C20ORF2; DIL-2; DIL2; FLS353; GD:C20ORF1; HCA519; HCTP4; P100; REPP86 Swiss-Prot :
Q9ULW0 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TPX2 (Q330). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3016 TPX2 (Q330) pAb.
TPX2 (Q330) Peptide Applications :
Blocking Background :
TPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 for the chromatin-induced microbutule assembly during M phase. Aurora-A kinase associates with TPX2 at the spindle apparatus and may regulate TPX2 via phosphorylation during the spindle assembly. TPX2 appears to play a structural role in spindle formation. TPX2 activates Eg2 in a microtubuledependent manner by stimulating the phosphorylation and kinase activity of Eg2. TPX2 is inactivated by binding to importin α, a nuclear import factor. Finally, the suppression of TPX2 with RNA interference causes defects in microtubule organization during mitosis. Alternative Name :
TPX2; C20ORF1; C20ORF2; DIL-2; DIL2; FLS353; GD:C20ORF1; HCA519; HCTP4; P100; REPP86 Swiss-Prot :
Q9ULW0 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TPX2 (Q330). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3016 TPX2 (Q330) pAb.
Blocking peptide available as BS3016PP