GnTα4 (H65) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
GnTα4 (H65) Peptide Applications :
Blocking Background :
Alpha 1,4-N-acetylflucosaminyltransferase (α4Gn-T) mediates the biosynthesis of mucin type glycoprotein (O-glycan). α4Gn-T acts as the key enzyme for the formation of the unique glycan GlcNAcα1-4Galβ1-R, and most efficiently transfers N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. α4Gn-T is a single-pass type II membrane protein associated with the Golgi apparatus and contains the conserved DXD motif involved in catalytic activity. It is expressed in stomach and pancreas, as well as in gastric cancer cells. α4Gn-T is not expressed in peripheral blood cells, making it a useful biomarker for pancreatic cancer. α4Gn-T and Mucin 6 expression is upregulated in the gastric mucosa of H. pylori infected patients, which suggest the involvement of α4Gn-T in defense against H. pylori infection. Alternative Name :
Alpha-1;4-N-acetylglucosaminyltransferase; α4GnT; A4GNT; GnTα4; α4 GnT Swiss-Prot :
Q9UNA3 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide GnTα4 (H65). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3069 GnTα4 (H65) pAb.
GnTα4 (H65) Peptide Applications :
Blocking Background :
Alpha 1,4-N-acetylflucosaminyltransferase (α4Gn-T) mediates the biosynthesis of mucin type glycoprotein (O-glycan). α4Gn-T acts as the key enzyme for the formation of the unique glycan GlcNAcα1-4Galβ1-R, and most efficiently transfers N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. α4Gn-T is a single-pass type II membrane protein associated with the Golgi apparatus and contains the conserved DXD motif involved in catalytic activity. It is expressed in stomach and pancreas, as well as in gastric cancer cells. α4Gn-T is not expressed in peripheral blood cells, making it a useful biomarker for pancreatic cancer. α4Gn-T and Mucin 6 expression is upregulated in the gastric mucosa of H. pylori infected patients, which suggest the involvement of α4Gn-T in defense against H. pylori infection. Alternative Name :
Alpha-1;4-N-acetylglucosaminyltransferase; α4GnT; A4GNT; GnTα4; α4 GnT Swiss-Prot :
Q9UNA3 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide GnTα4 (H65). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3069 GnTα4 (H65) pAb.
Blocking peptide available as BS3069PP