AQP12 (P265) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
AQP12 (P265) Peptide Applications :
Blocking Background :
Aquaporin 12 (AQP12) is the most recently identified member of the mammalian AQP family and is specifically expressed in pancreatic acinar cells. In vitro expression studies have revealed that AQP12 is localized at intracellular sites. To determine the physiological roles of AQP12 in the pancreas, we generated knockout mice for this gene (AQP12-KO). No obvious differences were observed under normal conditions between wild-type (WT) and AQP12-KO mice in terms of growth, blood chemistry, pancreatic fluid content, or histology. However, when we induced pancreatitis through the administration of a cholecystokinin-8 (CCK-8) analog, the AQP12-KO mice showed more severe pathological damage to this organ than WT mice. Alternative Name :
Aquaporin-12A; AQP-12; AQP12A; AQP12; AQPX2; Aquaporin-12B; AQP-12B; AQP12B Swiss-Prot :
Q8IXF9/A6NM10 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide AQP12 (P265). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3075 AQP12 (P265) pAb.
AQP12 (P265) Peptide Applications :
Blocking Background :
Aquaporin 12 (AQP12) is the most recently identified member of the mammalian AQP family and is specifically expressed in pancreatic acinar cells. In vitro expression studies have revealed that AQP12 is localized at intracellular sites. To determine the physiological roles of AQP12 in the pancreas, we generated knockout mice for this gene (AQP12-KO). No obvious differences were observed under normal conditions between wild-type (WT) and AQP12-KO mice in terms of growth, blood chemistry, pancreatic fluid content, or histology. However, when we induced pancreatitis through the administration of a cholecystokinin-8 (CCK-8) analog, the AQP12-KO mice showed more severe pathological damage to this organ than WT mice. Alternative Name :
Aquaporin-12A; AQP-12; AQP12A; AQP12; AQPX2; Aquaporin-12B; AQP-12B; AQP12B Swiss-Prot :
Q8IXF9/A6NM10 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide AQP12 (P265). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3075 AQP12 (P265) pAb.
Blocking peptide available as BS3075PP