Arfaptin 1 (K314) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Arfaptin 1 (K314) Peptide Applications :
Blocking Background :
Arfaptin 1 is an ARF binding protein that inhibits PLD activation, vesicular trafficking and secretion. In the present report, we show that arfaptin 1 interacts with 'high speed' membranes independently of ARF. However, addition of myristoylated ARF3 (myrARF3) increases the association of arfaptin 1 with the membranes, suggesting that arfaptin 1 and ARF form a complex on the Golgi. Utilizing several deletion mutants of arfaptin 1 it is shown that the association of arfaptin 1 with myrARF3 is mediated via two binding sites on arfaptin 1. These two domains are needed for arfaptin 1 inhibition of PLD activation by myrARF3 in vitro. Alternative Name :
Arfaptin-1; ADP-ribosylation factor-interacting protein 1; ARFIP1; Arfaptin1 Swiss-Prot :
P53367 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Arfaptin 1 (K314). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3076 Arfaptin 1 (K314) pAb.
Arfaptin 1 (K314) Peptide Applications :
Blocking Background :
Arfaptin 1 is an ARF binding protein that inhibits PLD activation, vesicular trafficking and secretion. In the present report, we show that arfaptin 1 interacts with 'high speed' membranes independently of ARF. However, addition of myristoylated ARF3 (myrARF3) increases the association of arfaptin 1 with the membranes, suggesting that arfaptin 1 and ARF form a complex on the Golgi. Utilizing several deletion mutants of arfaptin 1 it is shown that the association of arfaptin 1 with myrARF3 is mediated via two binding sites on arfaptin 1. These two domains are needed for arfaptin 1 inhibition of PLD activation by myrARF3 in vitro. Alternative Name :
Arfaptin-1; ADP-ribosylation factor-interacting protein 1; ARFIP1; Arfaptin1 Swiss-Prot :
P53367 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Arfaptin 1 (K314). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3076 Arfaptin 1 (K314) pAb.
Blocking peptide available as BS3076PP