CLN6 (N258) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
CLN6 (N258) Peptide Applications :
Blocking Background :
CLN6, a 311-amino acid protein, has 7 predicted transmembrane domains and is conserved across vertebrates. The CLN6 protein localizes to the endoplasmic reticulum but contributes to lysosomal function. Mutations in the CLN6 gene cause variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL), a lysosomal storage disorder marked by progressive mental deterioration and blindness; part of a group of severe inherited neurodegenerative disorders affecting children wherein lysosomes accumulate storage material, causing the death of neurons. CLN6 is one of eight proteins, including CLN1-8, that are associated with NCL. Alternative Name :
Ceroid-lipofuscinosis neuronal protein 6; Protein CLN6; CLN6 Swiss-Prot :
Q9NWW5 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CLN6 (N258). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3102 CLN6 (N258) pAb.
CLN6 (N258) Peptide Applications :
Blocking Background :
CLN6, a 311-amino acid protein, has 7 predicted transmembrane domains and is conserved across vertebrates. The CLN6 protein localizes to the endoplasmic reticulum but contributes to lysosomal function. Mutations in the CLN6 gene cause variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL), a lysosomal storage disorder marked by progressive mental deterioration and blindness; part of a group of severe inherited neurodegenerative disorders affecting children wherein lysosomes accumulate storage material, causing the death of neurons. CLN6 is one of eight proteins, including CLN1-8, that are associated with NCL. Alternative Name :
Ceroid-lipofuscinosis neuronal protein 6; Protein CLN6; CLN6 Swiss-Prot :
Q9NWW5 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CLN6 (N258). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3102 CLN6 (N258) pAb.
Blocking peptide available as BS3102PP