KDEL Receptor 3 (L95) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
KDEL Receptor 3 (L95) Peptide Applications :
Blocking Background :
Soluble proteins in the endoplasmic reticulum (ER) contain a specific carboxy terminal sequence KDEL (Lys-Asp-Glu-Leu), and include the coat proteins required for vesicle budding from the ER, proteins that form retrogradevesicles on post-ER compartments, and integral membrane proteins that target vesicles to their correct destination. The retention of these soluble proteins in the ER depends on the interaction of the KDEL sequence with the corresponding KDEL receptor, also designated ERD2, in the Golgi apparatus.When KDEL proteins reach the Golgi complex, they are recognized by the KDEL receptor and transported retrograde in COPI-coated vesicles back to the ER. The small GTPase ADP-ribosylation factor 1 (ARF1), a regulator of vesicle transport, interacts with the KDEL receptor. Alternative Name :
ER lumen protein retaining receptor 3; KDEL endoplasmic reticulum protein retention receptor 3; Short name=KDEL receptor 3; KDELR3 Swiss-Prot :
O43731 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide KDEL Receptor 3 (L95). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3124 KDEL Receptor 3 (L95) pAb.
KDEL Receptor 3 (L95) Peptide Applications :
Blocking Background :
Soluble proteins in the endoplasmic reticulum (ER) contain a specific carboxy terminal sequence KDEL (Lys-Asp-Glu-Leu), and include the coat proteins required for vesicle budding from the ER, proteins that form retrogradevesicles on post-ER compartments, and integral membrane proteins that target vesicles to their correct destination. The retention of these soluble proteins in the ER depends on the interaction of the KDEL sequence with the corresponding KDEL receptor, also designated ERD2, in the Golgi apparatus.When KDEL proteins reach the Golgi complex, they are recognized by the KDEL receptor and transported retrograde in COPI-coated vesicles back to the ER. The small GTPase ADP-ribosylation factor 1 (ARF1), a regulator of vesicle transport, interacts with the KDEL receptor. Alternative Name :
ER lumen protein retaining receptor 3; KDEL endoplasmic reticulum protein retention receptor 3; Short name=KDEL receptor 3; KDELR3 Swiss-Prot :
O43731 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide KDEL Receptor 3 (L95). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3124 KDEL Receptor 3 (L95) pAb.
Blocking peptide available as BS3124PP