MED18 (V102) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
MED18 (V102) Peptide Applications :
Blocking Background :
In mammalian cells, transcription is regulated in part by high molecular weight co-activating complexes that mediate signals between transcriptional activators and RNA polymerase II (Pol II). The mediator complex is one such multi-protein structure that functions as a bridge between regulatory proteins and Pol II, thereby regulating Pol II-dependent transcription. Med18 (mediator complex subunit 18), also known asp28b, is a 208 amino acid protein that localizes to nucleus and exists as a component of the mediator complex. Working in tandem with several other proteins, including Med8 and Med25, Med18 serves as a scaffold for the assembly of a functional preinitiation complex with Pol II and general transcription factors, thereby activating the transcription of Pol II-dependent genes. Alternative Name :
Mediator of RNA polymerase II transcription subunit 18; Mediator complex subunit 18; p28b; MED18 Swiss-Prot :
Q9BUE0 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide MED18 (V102). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3141 MED18 (V102) pAb.
MED18 (V102) Peptide Applications :
Blocking Background :
In mammalian cells, transcription is regulated in part by high molecular weight co-activating complexes that mediate signals between transcriptional activators and RNA polymerase II (Pol II). The mediator complex is one such multi-protein structure that functions as a bridge between regulatory proteins and Pol II, thereby regulating Pol II-dependent transcription. Med18 (mediator complex subunit 18), also known asp28b, is a 208 amino acid protein that localizes to nucleus and exists as a component of the mediator complex. Working in tandem with several other proteins, including Med8 and Med25, Med18 serves as a scaffold for the assembly of a functional preinitiation complex with Pol II and general transcription factors, thereby activating the transcription of Pol II-dependent genes. Alternative Name :
Mediator of RNA polymerase II transcription subunit 18; Mediator complex subunit 18; p28b; MED18 Swiss-Prot :
Q9BUE0 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide MED18 (V102). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3141 MED18 (V102) pAb.
Blocking peptide available as BS3141PP