RAI3 (L179) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
RAI3 (L179) Peptide Applications :
Blocking Background :
Retinoic acid-induced protein 3 (RAI3) is a transmembrane G protein-coupled receptor that affects many essential biological processes including embryogenesis,cell growth, differentiation and apoptosis. RAI3 may also be involved in maintaining homeostasis of epithelial cells. Retinoic acid receptors directly regulate RAI3 during its transcription in embryonal carcinoma differentiation. RAI3 expression is upregulated in most tumor cell lines that express mutant p53, suggesting that p53 interacts with the promoter of RAI3 and represses its expression at the beginning of apoptosis. RAI3 is a potential molecular target for diagnosing breast cancer; selective suppression of signals from RAI3 may have a place in breast cancer treatments. Alternative Name :
Retinoic acid-induced gene 1 protein; RAIG-1; Orphan G-protein coupling receptor PEIG-1; GPRC5A; RAI3; RAIG1 Swiss-Prot :
Q8NFJ5 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide RAI3 (L179). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3199 RAI3 (L179) pAb.
RAI3 (L179) Peptide Applications :
Blocking Background :
Retinoic acid-induced protein 3 (RAI3) is a transmembrane G protein-coupled receptor that affects many essential biological processes including embryogenesis,cell growth, differentiation and apoptosis. RAI3 may also be involved in maintaining homeostasis of epithelial cells. Retinoic acid receptors directly regulate RAI3 during its transcription in embryonal carcinoma differentiation. RAI3 expression is upregulated in most tumor cell lines that express mutant p53, suggesting that p53 interacts with the promoter of RAI3 and represses its expression at the beginning of apoptosis. RAI3 is a potential molecular target for diagnosing breast cancer; selective suppression of signals from RAI3 may have a place in breast cancer treatments. Alternative Name :
Retinoic acid-induced gene 1 protein; RAIG-1; Orphan G-protein coupling receptor PEIG-1; GPRC5A; RAI3; RAIG1 Swiss-Prot :
Q8NFJ5 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide RAI3 (L179). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3199 RAI3 (L179) pAb.
Blocking peptide available as BS3199PP