DCC (F465) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
DCC (F465) Peptide Applications :
Blocking Background :
DCC (deleted in colorectal cancer) was first identified as a candidate tumor suppressor gene based on its absence or reduced expression in the majority of colorectal cancers. Loss of DCC expression was subsequently observed in cancers of the breast, endometrium, brain, pancreas and prostate, as well as in leukemias, neuroblastomas and male germ cell cancers. DCC is a 1447 amino acid transmembrane protein with highest expression in developing brain and neural tube and is suspected to play a role in mediating directional migration in the developing nervous system. Netrin-1, a chemoattractant for commissural axons in the spinal cord, has been identified as a ligand for DCC. Alternative Name :
Netrin receptor DCC,Colorectal cancer suppressor,Immunoglobulin superfamily DCC subclass member 1,Tumor suppressor protein DCC,IGDCC1,DCC Swiss-Prot :
P43146 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide DCC (F465) . (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3232 DCC (F465) pAb .
DCC (F465) Peptide Applications :
Blocking Background :
DCC (deleted in colorectal cancer) was first identified as a candidate tumor suppressor gene based on its absence or reduced expression in the majority of colorectal cancers. Loss of DCC expression was subsequently observed in cancers of the breast, endometrium, brain, pancreas and prostate, as well as in leukemias, neuroblastomas and male germ cell cancers. DCC is a 1447 amino acid transmembrane protein with highest expression in developing brain and neural tube and is suspected to play a role in mediating directional migration in the developing nervous system. Netrin-1, a chemoattractant for commissural axons in the spinal cord, has been identified as a ligand for DCC. Alternative Name :
Netrin receptor DCC,Colorectal cancer suppressor,Immunoglobulin superfamily DCC subclass member 1,Tumor suppressor protein DCC,IGDCC1,DCC Swiss-Prot :
P43146 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide DCC (F465) . (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3232 DCC (F465) pAb .
Blocking peptide available as BS3232PP