PD2R (E301) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
PD2R (E301) Peptide Applications :
Blocking Background :
The prostaglandin D2 receptor is a member of the G-protein-coupled receptor (GPCR) family (subfamily: prostanoid). It has been shown to function as a prostanoid DP receptor. Its activity is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses. Prostaglandin D2 receptor has been reported to be expressed in human small intestine, colon (goblet cells), eye, and eosinophils. ESTs have been isolated from human brain libraries. Alternative Name :
Prostaglandin D2 receptor; PGD receptor; PGD2 receptor; Prostanoid DP receptor; PTGDR Swiss-Prot :
Q13258 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PD2R (E301). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3239 PD2R (E301) pAb.
PD2R (E301) Peptide Applications :
Blocking Background :
The prostaglandin D2 receptor is a member of the G-protein-coupled receptor (GPCR) family (subfamily: prostanoid). It has been shown to function as a prostanoid DP receptor. Its activity is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses. Prostaglandin D2 receptor has been reported to be expressed in human small intestine, colon (goblet cells), eye, and eosinophils. ESTs have been isolated from human brain libraries. Alternative Name :
Prostaglandin D2 receptor; PGD receptor; PGD2 receptor; Prostanoid DP receptor; PTGDR Swiss-Prot :
Q13258 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PD2R (E301). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3239 PD2R (E301) pAb.
Blocking peptide available as BS3239PP